Journal2005
A Novel Method for the One-Pot Three-Component Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones
Synlett No. 7, 1155–1157
چکیده
One-pot three-component condensation of isatoic anhydride with primary amines or ammonium carbonate and aromatic aldehydes in refluxing ethanol in the presence of catalytic amounts of silica sulfuric acid afforded the corresponding 2,3-dihydroquinazolin-4(1H)-ones in high yields. The catalyst is reusable and can be applied several times without any decrease in product yield.
موضوعات و کلیدواژهها
Quinazolinone synthesis and applicationsMulticomponent Synthesis of HeterocyclesSynthesis and Reactivity of Heterocycles23-dihydroquinazolin-4(1H)-onesone-pot three-component reactionisatoic anhydrideprimary aminesammonium carbonatearomatic aldehydessilica sulfuric acidheterogeneous acid catalysiscatalyst reusability
ارجاع علمی
Peyman Salehi, Minoo Dabiri, Mohammad Ali Zolfigol, Mostafa Baghbanzadeh. “A Novel Method for the One-Pot Three-Component Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones.” Synlett, 2005. https://doi.org/10.1055/s-2005-865200