Journal2010
An Efficient Protocol for the Synthesis of Carboacyclic Nucleosides via Aza -Conjugate Addition Reaction
Vol. 29, No. 4, 67–73
چکیده
ABSTRACT: A new efficient method for the synthesis of carboacyclic nucleosides as biologically interesting compounds via aza-conjugate addition of pyrimidine nucleobases to α,-unsaturated esters in the presence of catalytic amount of LiOH.H2O (1.2-4.8 mol%) under microwave irradiation is described. This method affords the title compounds in good to excellent yields and in short reaction times.
موضوعات و کلیدواژهها
Synthesis and Characterization of Heterocyclic CompoundsMulticomponent Synthesis of HeterocyclesSynthesis and Biological EvaluationConjugateMicrowave irradiationPyrimidineNucleobaseCatalysisChemistryCombinatorial chemistryOrganic chemistryStereochemistryDNAMathematicsBiochemistry
ارجاع علمی
Mohammad Ali Zolfigol, Ardeshir Khazaei, Abdolkarim Zare, Hasanijejad Ali Reza. “An Efficient Protocol for the Synthesis of Carboacyclic Nucleosides via Aza -Conjugate Addition Reaction.” , 2010. https://doi.org/10.30492/ijcce.2010.6406