Journal2022دسترسی آزاد
Catalytic synthesis of new pyrazolo [3,4-b] pyridine via a cooperative vinylogous anomeric-based oxidation
Scientific Reports Vol. 12, No. 1, 14145–14145
چکیده
Abstract In this study, a novel nano-magnetic metal–organic frameworks based on Fe3O4 namely Fe3O4@MIL-101(Cr)-N(CH2PO3)2 was synthesized and fully characterized. The prepared sample was used as catalyst in the synthesis of pyrazolo [3,4-b] pyridines as convenient medicine by condensation reaction of aldehydes, 5-(1H-Indol-3-yl)- 2H-pyrazol-3-ylamine and 3-(cyanoacetyl)indole via a CVABO. The products were obtained with high yields at 100 °C and under solvent-free conditions.
موضوعات و کلیدواژهها
Multicomponent Synthesis of HeterocyclesMetal-Organic Frameworks: Synthesis and ApplicationsSynthesis of Indole Derivativespyrazolo[34-b]pyridinescatalytic synthesismagnetic metal-organic frameworksnanozymessolvent-free synthesiscondensation reactionsaldehydes
ارجاع علمی
Hassan Sepehrmansourie, Mahmoud Zarei, Mohammad Ali Zolfigol, Saeed Babaee, Saeid Azizian, Sadegh Rostamnia. “Catalytic synthesis of new pyrazolo [3,4-b] pyridine via a cooperative vinylogous anomeric-based oxidation.” Scientific Reports, 2022. https://doi.org/10.1038/s41598-022-17879-5