Journal2006دسترسی آزاد
Microwave-assisted Synthesis of N-Arylglycines: Improvement of Sydnone Synthesis
Heterocycles Vol. 68, No. 1, 175–175
چکیده
Reactions of anilines with ethyl bromoacetate under microwave irradiation have afforded N-arylglycines that are subsequently converted to their N-nitroso derivatives with a combination of silica chloride or periodic acid, wet SiO 2 and sodium nitrite in CH 2 Cl 2 with satisfactory yields.In the final step, the use of 1,3-dibromo-5,5-dimethylhydantoin (DBH) as a new and effective reagent for dehydration of N-nitroso-N-arylglycines to sydnones was successfully examined.
موضوعات و کلیدواژهها
N-Heterocyclic Carbenes in Organic and Inorganic ChemistryMicrowave-Assisted Synthesis and ApplicationsQuinazolinone synthesis and applicationsChemistryReagentEthyl bromoacetateSodium nitriteMicrowave irradiationNitrosoSydnoneNuclear chemistryDehydrationChlorideNitroso CompoundsOrganic chemistrySodiumNitriteNitrateCatalysisRing (chemistry)
ارجاع علمی
Davood Azarifar, Hassan Ghasemnejad Bosra, Mohammad Ali Zolfigol, Mahmood Tajbaksh. “Microwave-assisted Synthesis of N-Arylglycines: Improvement of Sydnone Synthesis.” Heterocycles, 2006. https://doi.org/10.3987/com-05-10574