Journal2010

Protection of hydroxy groups as trimethylsilyl ethers using 1,1,1,3,3,3-hexamethyldisilazane (HMDS) catalyzed by poly(4-vinylpyridinium tribromide)

Arash Ghorbani‐Choghamarani, Mohammad Ali Zolfigol, Maryam Hajjami, Khorshid Darvishi, Laleh Gholamnia

Collection of Czechoslovak Chemical Communications Vol. 75, No. 5, 607–615

چکیده

A very efficient procedure for the protection of alcohols and phenols is presented. The mixture of 1,1,1,3,3,3-hexamethyldisilazane (HMDS) and catalytic amounts of poly(4-vinylpyridinium tribromide) was found to be effective for the trimethylsilylation of alcohols and phenols. Protection reaction is very simple and performs heterogeneously in acetonitrile at room temperature under mild conditions.

موضوعات و کلیدواژه‌ها

Chemical Synthesis and ReactionsEnvironmental Chemistry and AnalysisSulfur-Based Synthesis TechniquesTribromidePhenolsChemistryAcetonitrileCatalysisTrimethylsilylOrganic chemistry

ارجاع علمی

Arash Ghorbani‐Choghamarani, Mohammad Ali Zolfigol, Maryam Hajjami, Khorshid Darvishi, Laleh Gholamnia. “Protection of hydroxy groups as trimethylsilyl ethers using 1,1,1,3,3,3-hexamethyldisilazane (HMDS) catalyzed by poly(4-vinylpyridinium tribromide).” Collection of Czechoslovak Chemical Communications, 2010. https://doi.org/10.1135/cccc2009560