Journal2011دسترسی آزاد
Synthesis and Crystal Structure Determination of [H2‐cryptand 222](Br3)2: A Unique Tribromide Catalyst for the Catalytic Chemoselective N‐Boc Protection of Amines
Journal of the Chinese Chemical Society Vol. 58, No. 4, 538–543
چکیده
Abstract The organic tribromide, [H2‐cryptand 222](Br3)2 was synthesized and characterized by X‐ray crystallography, and was utilized as an active catalyst for the N‐boc protection of amines. The method is general for the preparation of N‐boc derivatives of aliphatic (acyclic and cyclic), aromatic, primary and secondary amines. We also applied our new reaction protocols for the N‐boc protection of some new amines and spectral and physical data for the obtained products are reported.
موضوعات و کلیدواژهها
Chemical Synthesis and ReactionsChemical Synthesis and AnalysisSynthesis and Catalytic ReactionsChemistryTribromideCryptandCatalysisPrimary (astronomy)Crystal structureCyclic aminesOrganic chemistryMedicinal chemistry
ارجاع علمی
Gholamabbas Chehardoli, Mohammad Ali Zolfigol, Vahid Khakyzadeh, Reza Golbedaghi, Nikita Hall, Allan G. Blackman. “Synthesis and Crystal Structure Determination of [H2‐cryptand 222](Br3)2: A Unique Tribromide Catalyst for the Catalytic Chemoselective N‐Boc Protection of Amines.” Journal of the Chinese Chemical Society, 2011. https://doi.org/10.1002/jccs.201190018