Journal2013
Synthesis of 2,4,6-Triarylpyridines Using ZrOCl2 under Solvent-Free Conditions
Synlett Vol. 25, No. 02, 193–196
چکیده
An efficient procedure for the synthesis of 2,4,6-triarylpyridines (Kröhnke pyridines) by the one-pot multicomponent condensation of aldehydes (1 equiv) with acetophenones (2 equiv) and ammonium acetate (1.2 equiv) in the presence of catalytic amounts of oxozirconium(IV) chloride (ZrOCl 2 ) under solvent-free conditions is described. In this work, four products have been reported for the first time. Easy work-up, simple methodology, clean reaction and reusability of the catalyst are some advantages of this work.
موضوعات و کلیدواژهها
Multicomponent Synthesis of HeterocyclesSynthesis of heterocyclic compoundsChemical Synthesis and Reactions246-triarylpyridinessolvent-free synthesisaldehydesacetophenoneammonium acetatezirconium catalystscatalyst reusability
ارجاع علمی
Ahmad Reza Moosavi‐Zare, Mohammad Ali Zolfigol, Shohreh Farahmand, Abdolkarim Zare, Ali Reza Pourali, Roya Ayazi‐Nasrabadi. “Synthesis of 2,4,6-Triarylpyridines Using ZrOCl2 under Solvent-Free Conditions.” Synlett, 2013. https://doi.org/10.1055/s-0033-1340088