Journal2013
Synthesis of 2,4,6-Triarylpyridines Using ZrOCl2 under Solvent-Free Conditions
Synlett Vol. 25, No. 02, 193–196
چکیده
An efficient procedure for the synthesis of 2,4,6-triarylpyridines (Kröhnke pyridines) by the one-pot multicomponent condensation of aldehydes (1 equiv) with acetophenones (2 equiv) and ammonium acetate (1.2 equiv) in the presence of catalytic amounts of oxozirconium(IV) chloride (ZrOCl 2 ) under solvent-free conditions is described. In this work, four products have been reported for the first time. Easy work-up, simple methodology, clean reaction and reusability of the catalyst are some advantages of this work.
موضوعات و کلیدواژهها
Multicomponent Synthesis of HeterocyclesSynthesis of Tetrazole DerivativesSynthesis and Characterization of Heterocyclic CompoundsChemistryCatalysisReusabilityAmmonium acetateCondensationSolventAmmonium chlorideOrganic chemistryChlorideCombinatorial chemistryProgramming language
ارجاع علمی
Ahmad Reza Moosavi‐Zare, Mohammad Ali Zolfigol, Shohreh Farahmand, Abdolkarim Zare, Ali Reza Pourali, Roya Ayazi‐Nasrabadi. “Synthesis of 2,4,6-Triarylpyridines Using ZrOCl2 under Solvent-Free Conditions.” Synlett, 2013. https://doi.org/10.1055/s-0033-1340088