Journal2008

Vanadium Hydrogen Sulfate (I): Chemoselective Trimethylsilylation of Alcohols and Deprotection of Trimethylsilyl Ethers

Farhad Shirini, Mohammad Ali Zolfigol, Masoumeh Abedini, Ali Reza Sakhaei

Journal of the Chinese Chemical Society Vol. 55, No. 5, 943–946

چکیده

Abstract Trimethylsilylation of alcohols with hexamethyldisilazane (HMDS) catalyzed by V(HSO4)3 under mild and completely heterogeneous reaction condition is reported. The method is highly chemoselective for the protection of alcohols in the presence of phenols, amines and thiols. Also, the deprotection of trimethylsilyl ethers is performed in the presence of V(HSO4)3 at room temperature in good to high yields.

موضوعات و کلیدواژه‌ها

Chemical Synthesis and ReactionsSulfur-Based Synthesis TechniquesOxidative Organic Chemistry ReactionsChemistryTrimethylsilylPhenolsSilylationVanadiumOrganic chemistrySulfateCatalysisHydrogen SulfateHydrogen

ارجاع علمی

Farhad Shirini, Mohammad Ali Zolfigol, Masoumeh Abedini, Ali Reza Sakhaei. “Vanadium Hydrogen Sulfate (I): Chemoselective Trimethylsilylation of Alcohols and Deprotection of Trimethylsilyl Ethers.” Journal of the Chinese Chemical Society, 2008. https://doi.org/10.1002/jccs.200800140